BoneMarrowMononuclearCells(BMMC)arelocatedinthebonemarrowandhaveregenerativecapABIlities.PrimaryBMMCareaheterogeneouspopulationofsinglenucleuscellswhichincludehematopoieticstemcells,hematopoieticProgenitorcells,immaturemonocytes,andimmaturelymphocytes[1].RecentstudiessuggestthatBMMCaresuitableasacelltherapytotreatavarietyofdiseasessuchascardiovasculardisease,type1diabetes,andischemicstroke[2,3,4].BMMCmayalsobeusedforbonetissueengineering[1].PrimarymouseBMMC(MBMMC)canbeutilizedtofurtherstudyBMMCasapotentialcelltherapy.
MBMMCfromScienCellResearchLaboratoriesareisolatedfromhealthyadultCD-1mousebonemarrow.MBMMCaredepletedoferythrocytesandbonemarrowmacrophages,cryopreservedimmediatelyafterisolation,anddeliveredfrozen.MBMMCareamixedpopulationofcellsthatincludehematopoieticstemcellsandprogenitorcells,monocytes,andlymphocytes.Eachvialcontainsatleast10millioncellsin1mlvolume.MBMMCarequalitycontroltestedforviability.MBMMCarenegativeformycoplasma,bacteria,yeast,andfungi.MBMMCcanbemaintainedforashortperiodoftimeincultureusingtheconditionsprovidedbyScienCellResearchLaboratoriesandarenotintendedforlong-termculture.
Specifications:
CatalogNo. | M1930 |
CountryofManufacture | UnitedStates |
ProductCode | MBMMC |
Size/Quantity | 10millioncellsin1mlvolume |
ProductUse | MBMMCareforresearchuseonly.Theyarenotapprovedforhumanoranimaluse,orforapplicationininvitrodiagnosticprocedures. |
Storage | Uponreceiving,directlyandimmediatelytransferthecellsfromdryicetoliquidnitrogenandkeepthecellsinliquidnitrogenuntiltheyareneededforexperiments. |
ShippingInfo | Dryice. |
References | [1]HenrichD,VerboketR,SchaIBLeA,KontradowitzK,OppermannE,BruneJ,NauC,MeierS,BonigH,MarziI,SeebachC.(2015)"CharacterizationofbonemarrowmononuclearcellsonBiomaterialsforbonetissueengineeringinvitro."BiomedResInt.10:1-12.[2]SavitzS,MisraV,KasamM,JunejaH.,CoxC,AldermanS,etal.(2011)."Intravenousautologousbonemarrowmononuclearcellsforischemicstroke."AnnNeurol.70:59-69.[3]FotinoC,RicordiC,LauriolaV,AlejandroR,PileggiA.(2010)"Bonemarrow-derivedstemcelltransplantationforthetreatmentofinsulin-dependentdiabetes."RevDiabetStud.7(2):144-157.[4]ArnousS,MozidA,MartinJ,MathurA.(2012)"Bonemarrowmononuclearcellsandacutemyocardialinfarction."StemCellRes.3(1):2-10. |